6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide

Base Information

• Chemical Name: 6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide
• CAS No.: 368884-31-5
• Molecular Formula: BrH*C₂₂H₂₁BrN₂O₂
• Molecular Weight: 506.237

Synonyms:6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide

Chemical Property of 6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide

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Technology Process of 6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide

There total 1 articles about 6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(methoxymethyl)-2,3,4-trihydronaphthalen-1-one (368880-28-8) → 6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide (368884-31-5)

Guidance literature:

With hydrogen bromide; In acetic acid;

Reference yield:

6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide (368884-31-5) + phenol (108-95-2,27073-41-2) → 6-((1S)-2-Imidazolyl-1-phenylethoxy)-5-(phenoxymethyl)-2,3,4-trihydronaphthalen-1-one (368880-30-2)

Guidance literature:

With ammonia; In tetrahydrofuran; methanol; acetonitrile;

Reference yield:

6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(bromomethyl)-2,3,4-trihydronaphthalen-1-one hydrobromide (368884-31-5) + 4-Trifluoromethoxyphenol (828-27-3) → 6-((1S)-2-Imidazolyl-1-phenylethoxy)-5-{[4-(trifluoromethoxy) phenoxy]methyl}-2,3,4-trihydronaphthalen-1-one (368881-47-4)

Guidance literature:

In tetrahydrofuran; acetonitrile;

upstream raw materials:

6-((1S)-2-imidazolyl-1-phenylethoxy)-5-(methoxymethyl)-2,3,4-trihydronaphthalen-1-one

Downstream raw materials:

6-((1S)-2-Imidazolyl-1-phenylethoxy)-5-{[4-(trifluoromethoxy) phenoxy]methyl}-2,3,4-trihydronaphthalen-1-one

6-((1S)-2-imidazolyl-1-phenylethoxy)-5-[(3,5-dimethoxyphenoxy) methyl]-2,3,4-trihydronaphthalen-1-one

6-((S)-2-Imidazol-1-yl-1-phenyl-ethoxy)-5-(4-phenyl-piperazin-1-ylmethyl)-3,4-dihydro-2H-napthalen-1-one

6-((S)-2-Imidazol-1-yl-1-phenyl-ethoxy)-5-(4-pyridin-2-yl-piperazin-1-ylmethyl)-3,4-dihydro-2H-napthalen-1-one

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