7-fluoroheptyl tosylate

Base Information

• Chemical Name: 7-fluoroheptyl tosylate
• CAS No.: 690228-48-9
• Molecular Formula: C₁₄H₂₁FO₃S
• Molecular Weight: 288.383
• Mol file: 690228-48-9.mol

Synonyms:7-fluoroheptyl tosylate

Chemical Property of 7-fluoroheptyl tosylate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 7-fluoroheptyl tosylate

There total 3 articles about 7-fluoroheptyl tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

heptane-1,7-diyl bis(4-methylbenzenesulfonate) (40235-95-8) → 7-fluoroheptyl tosylate (690228-48-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In acetonitrile; at 85 ℃; for 4h;

DOI:10.1002/jlcr.747

Reference yield:

1,7-heptandiol (629-30-1) → 7-fluoroheptyl tosylate (690228-48-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / pyridine / 3.25 h / 0 - 20 °C

2: 31 percent / tetrabutylammonium fluoride / acetonitrile / 4 h / 85 °C

With pyridine; tetrabutyl ammonium fluoride; In acetonitrile;

DOI:10.1002/jlcr.747

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 7-fluoroheptyl tosylate (690228-48-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / pyridine / 3.25 h / 0 - 20 °C

2: 31 percent / tetrabutylammonium fluoride / acetonitrile / 4 h / 85 °C

With pyridine; tetrabutyl ammonium fluoride; In acetonitrile;

DOI:10.1002/jlcr.747

upstream raw materials:

heptane-1,7-diyl bis(4-methylbenzenesulfonate)

1,7-heptandiol

p-toluenesulfonyl chloride

Refernces