2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide

Base Information

Chemical Name:2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide
CAS No.:639083-01-5
Molecular Formula:C₃₃H₄₂N₄O₆S
Molecular Weight:622.786
Hs Code.:

Synonyms:2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide

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Chemical Property of 2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide

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Technology Process of 2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide

There total 1 articles about 2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 246262-39-5
(R)-N-[5-[2-iodo-1-[(triethylsilyl)-oxy]ethyl]-2-(phenylmethoxy)phenyl]methanesulfonamide

: 244081-40-1
(2R)-[3-(2-aminopropyl)-1H-indol-7-yloxy]-N,N-diethylacetamide

: 639083-01-5
2-(3-{(2R)-2-[2-(4-benzyloxy-3-methanesulfonylaminophenyl)-(2R)-2-hydroxyethylamino]propyl}-1H-indol-7-yloxy)-N,N-diethylacetamide

Guidance literature:: (R)-N-[5-[2-iodo-1-[(triethylsilyl)-oxy]ethyl]-2-(phenylmethoxy)phenyl]methanesulfonamide; (2R)-[3-(2-aminopropyl)-1H-indol-7-yloxy]-N,N-diethylacetamide; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 110 ℃; for 18h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;