(Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate

Base Information

• Chemical Name: (Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate
• CAS No.: 1020031-82-6
• Molecular Formula: C₁₅H₂₄NO₄P
• Molecular Weight: 313.334
• Mol file: 1020031-82-6.mol

Synonyms:(Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate

Chemical Property of (Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate

There total 1 articles about (Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diethyl 3,6-dihydro-2-o-tolyl-1,2-oxazin-6-yl-6-phosphonate (1020031-74-6) → (Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate (1020031-82-6)

Guidance literature:

With acetic acid; zinc; In water;

DOI:10.1021/jo100230r

Reference yield: 75.0%

(Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate (1020031-82-6) → diethyl 2,5-dihydro-1-o-tolyl-1-pyrrol-2-yl-2-phosphonate (1020031-83-7)

Guidance literature:

With 1H-imidazole; carbon tetrabromide; triethylamine; triphenylphosphine; In dichloromethane; at 20 ℃; for 15h;

DOI:10.1016/j.tetlet.2008.01.050

Reference yield:

(Z)-diethyl 4-(o-tolylamino)-1-hydroxy-2-butenyl-1-phosphonate (1020031-82-6) → diethyl 4-(o-tolylamino)-1,2,3-trihydroxybutylphosphonate

Guidance literature:

With N-methyl-2-indolinone; potassium dioxotetrahydroxoosmate(VI); In water; acetone; at 20 ℃; for 24h;

DOI:10.1016/j.tetlet.2008.01.050

upstream raw materials:

diethyl 3,6-dihydro-2-o-tolyl-1,2-oxazin-6-yl-6-phosphonate

Downstream raw materials:

diethyl 2,5-dihydro-1-o-tolyl-1-pyrrol-2-yl-2-phosphonate

diethyl 1-hydroxybutylphosphonate