1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Base Information

Chemical Name:1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate
CAS No.:440105-06-6
Molecular Formula:C₃₆H₃₆O₇
Molecular Weight:580.678
Hs Code.:

Synonyms:1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Suppliers and Price of 1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

There total 7 articles about 1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 159425-38-4
2-<2-bromo-3-(benzyloxy)phenyl>-1,3-dioxane

: 3-benzyloxy-4-chlorocarbonyl-benzoic acid tert-butyl ester

: 440105-06-6
1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Guidance literature:: 2-<2-bromo-3-(benzyloxy)phenyl>-1,3-dioxane; With n-butyllithium; In tetrahydrofuran; at -68 ℃;

3-benzyloxy-4-chlorocarbonyl-benzoic acid tert-butyl ester; In tetrahydrofuran; at -68 ℃; for 3h; Further stages.;
DOI:10.1021/jm020018f

Reference yield:

: 14348-38-0
4-bromo-3-hydroxybenzoic acid

: 440105-06-6
1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 100 percent / K₂CO₃ / dimethylformamide / 72 h / 20 °C

2.1: 97 percent / aq. NaOH / methanol / 4 h / 60 °C

3.1: CDI / dimethylformamide / 3 h / 40 °C

3.2: 82 percent / DBU / dimethylformamide / 40 h / 55 °C

4.1: BuLi / tetrahydrofuran / -74 °C

4.2: 42 percent / tetrahydrofuran / 20 °C

5.1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 20 °C

6.1: BuLi / tetrahydrofuran / -68 °C

6.2: 37 percent / tetrahydrofuran / 3 h / -68 °C

With sodium hydroxide; n-butyllithium; oxalyl dichloride; potassium carbonate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm020018f

Reference yield:

: 17054-27-2
4-bromo-3-benzyloxybenzoic acid

: 440105-06-6
1,1-dimethylethyl 3-benzyloxy-4-[6-benzyloxy-2-(1,3-dioxan-2-yl)benzoyl]benzoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: CDI / dimethylformamide / 3 h / 40 °C

1.2: 82 percent / DBU / dimethylformamide / 40 h / 55 °C

2.1: BuLi / tetrahydrofuran / -74 °C

2.2: 42 percent / tetrahydrofuran / 20 °C

3.1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 20 °C

4.1: BuLi / tetrahydrofuran / -68 °C

4.2: 37 percent / tetrahydrofuran / 3 h / -68 °C

With n-butyllithium; oxalyl dichloride; 1,1'-carbonyldiimidazole; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm020018f