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2-Dimethylaminoisopropyl chloride hydrochloride

Base Information Edit
  • Chemical Name:2-Dimethylaminoisopropyl chloride hydrochloride
  • CAS No.:4584-49-0
  • Molecular Formula:C5H13Cl2N
  • Molecular Weight:158.071
  • Hs Code.:29211980
  • Mol file:4584-49-0.mol
2-Dimethylaminoisopropyl chloride hydrochloride

Synonyms:1-Propanamine,2-chloro-N,N-dimethyl-, hydrochloride (9CI);Propylamine,2-chloro-N,N-dimethyl-, hydrochloride (7CI,8CI);(2-Chloropropyl)dimethylaminehydrochloride;1-(Dimethylamino)-2-chloropropane hydrochloride;1-Dimethylamino-2-propylchloride hydrochloride;1-Dimethylaminopropan-2-yl chloride hydrochloride;1-Methyl-2-dimethylaminoethyl chloride hydrochloride;2-(Dimethylamino)isopropyl chloride hydrochloride;2-Chloro-N,N-dimethyl-1-propanamine hydrochloride;2-Chloro-N',N'-dimethylaminopropane hydrochloride;Dimethylaminoisopropyl chloride hydrochloride;N,N-Dimethyl-2-chloropropylaminehydrochloride;NSC 53532;NSC 5367;

Suppliers and Price of 2-Dimethylaminoisopropyl chloride hydrochloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 2-DimethylaminoisopropylChlorideHydrochloride
  • 100g
  • $ 195.00
  • TCI Chemical
  • 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T)
  • 500g
  • $ 200.00
  • TCI Chemical
  • 2-Chloro-1-(dimethylamino)propane Hydrochloride >98.0%(T)
  • 25g
  • $ 22.00
  • Sigma-Aldrich
  • 2-Chloro-N,N-dimethylpropylamine hydrochloride 98%
  • 100g
  • $ 28.00
  • Crysdot
  • 2-Chloro-N,N-dimethylpropan-1-aminehydrochloride 98%
  • 100g
  • $ 50.00
  • Biosynth Carbosynth
  • 2-Dimethylaminoisopropyl chloride hydrochloride
  • 250 g
  • $ 80.00
  • Biosynth Carbosynth
  • 2-Dimethylaminoisopropyl chloride hydrochloride
  • 2 kg
  • $ 340.00
  • Biosynth Carbosynth
  • 2-Dimethylaminoisopropyl chloride hydrochloride
  • 1 kg
  • $ 200.00
  • American Custom Chemicals Corporation
  • 2 CHLORO-N,N-DIMETHYLPROPANAMINE HYDROCHLORIDE 95.00%
  • 100G
  • $ 2456.91
  • Ambeed
  • 2-Chloro-N,N-dimethylpropan-1-aminehydrochloride 98%
  • 100g
  • $ 24.00
Total 171 raw suppliers
Chemical Property of 2-Dimethylaminoisopropyl chloride hydrochloride Edit
Chemical Property:
  • Appearance/Colour:Colourless to pale beige crystalline powder 
  • Vapor Pressure:83mmHg at 25°C 
  • Melting Point:187-190 °C(lit.) 
  • Boiling Point:81.1 °C at 760 mmHg 
  • Flash Point:2.9 °C 
  • PSA:3.24000 
  • LogP:1.97730 
  • Storage Temp.:Store at RT. 
  • Sensitive.:Hygroscopic 
  • Solubility.:2000g/l 
  • Water Solubility.:2000 g/L (20 º C) 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:1
  • Rotatable Bond Count:2
  • Exact Mass:157.0425048
  • Heavy Atom Count:8
  • Complexity:45.3
Purity/Quality:

98% *data from raw suppliers

2-DimethylaminoisopropylChlorideHydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn, IrritantXi 
  • Hazard Codes:Xn,Xi 
  • Statements: 22-36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C[NH+](C)C)Cl.[Cl-]
  • Uses 2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl, methadone and promethazine) Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.
Technology Process of 2-Dimethylaminoisopropyl chloride hydrochloride

There total 2 articles about 2-Dimethylaminoisopropyl chloride hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With thionyl chloride; In chloroform; at 0 - 20 ℃; for 1h; Reflux;
Guidance literature:
With thionyl chloride; at 60 ℃; for 24h;
DOI:10.3797/scipharm.aut-00-21
Refernces Edit
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