Benzofuran, 3-methyl-5-(trifluoromethyl)-

Base Information

Chemical Name:Benzofuran, 3-methyl-5-(trifluoromethyl)-
CAS No.:463976-22-9
Molecular Formula:C₁₀H₇F₃O
Molecular Weight:200.16
Hs Code.:
DSSTox Substance ID:DTXSID401282744

Synonyms:3-methyl-5-(trifluoromethyl)benzofuran;463976-22-9;Benzofuran, 3-methyl-5-(trifluoromethyl)-;SCHEMBL4446704;JEQNNAWQKPMCIR-UHFFFAOYSA-N;DTXSID401282744;MFCD27950967;AKOS040800141;SY310500;3-methyl-5-(trifluoromethyl)-1-benzofuran

Suppliers and Price of Benzofuran, 3-methyl-5-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Benzofuran, 3-methyl-5-(trifluoromethyl)-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:200.04489933
Heavy Atom Count:14
Complexity:214

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=COC2=C1C=C(C=C2)C(F)(F)F

Technology Process of Benzofuran, 3-methyl-5-(trifluoromethyl)-

There total 2 articles about Benzofuran, 3-methyl-5-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 463976-21-8
α,α,α-trifluoro-o-iodo-p-cresol

: 106-95-6
allyl bromide

: 463976-22-9
3-methyl-5-(trifluoromethyl)benzofuran

Guidance literature:: α,α,α-trifluoro-o-iodo-p-cresol; allyl bromide; With potassium carbonate; In N,N-dimethyl-formamide; for 3h;

With palladium diacetate; n-butylamine hydrochloride; sodium carbonate; sodium formate; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1021/jm050462t

Reference yield:

: 463976-21-8
α,α,α-trifluoro-o-iodo-p-cresol

: 463976-22-9
3-methyl-5-(trifluoromethyl)benzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate

2: sodium carbonate; palladium diacetate; tetrabutyl-ammonium chloride

With tetrabutyl-ammonium chloride; palladium diacetate; sodium carbonate; potassium carbonate;