2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Base Information

Chemical Name:2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine
CAS No.:137898-77-2
Molecular Formula:C₂₄H₃₀N₄O
Molecular Weight:390.528
Hs Code.:

Synonyms:2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Suppliers and Price of 2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

There total 7 articles about 2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 137898-56-7
N-cyclopentyl-6-nitro-N-<(4-nitrophenoxy)propyl>-2-quinolinemethanamine

: 137898-77-2
2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; ethyl acetate; for 3h; under 760 Torr;
DOI:10.1021/jm00115a010

Reference yield:

: 79096-54-1
1-(3-Chloropropoxy)-4-nitrobenzene

: 137898-77-2
2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: K₂CO₃, NaI / ethanol; acetonitrile / 24 h / 60 °C

2: 62 percent / K₂CO₃, NaI / ethanol; acetonitrile / 24 h / 60 °C

3: 49 percent / H₂ / PtO₂ / ethanol; ethyl acetate / 3 h / 760 Torr

With hydrogen; potassium carbonate; sodium iodide; platinum(IV) oxide; In ethanol; ethyl acetate; acetonitrile;
DOI:10.1021/jm00115a010

Reference yield:

: 76253-77-5
2-(chloromethyl)-6-nitroquinoline

: 137898-77-2
2-({[3-(4-Amino-phenoxy)-propyl]-cyclopentyl-amino}-methyl)-quinolin-6-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / K₂CO₃, NaI / ethanol; acetonitrile / 24 h / 60 °C

2: 49 percent / H₂ / PtO₂ / ethanol; ethyl acetate / 3 h / 760 Torr

With hydrogen; potassium carbonate; sodium iodide; platinum(IV) oxide; In ethanol; ethyl acetate; acetonitrile;
DOI:10.1021/jm00115a010