(2-Iodophenyl)methanesulphonyl chloride

Base Information

• Chemical Name: (2-Iodophenyl)methanesulphonyl chloride
• CAS No.: 25068-94-4
• Molecular Formula: C₇H₆ClIO₂S
• Molecular Weight: 316.547
• Hs Code.: 2904990090
• Mol file: 25068-94-4.mol

Synonyms:(2-iodo-phenyl)-methanesulfonyl chloride

Chemical Property of (2-Iodophenyl)methanesulphonyl chloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-Iodophenyl)methanesulphonyl chloride

There total 2 articles about (2-Iodophenyl)methanesulphonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-(2-iodobenzyl)isothiouronium chloride → (2-iodo-phenyl)-methanesulfonyl chloride (25068-94-4)

Guidance literature:

With water; chlorine; In tetrahydrofuran; at 5 ℃;

Reference yield:

→ (2-iodo-phenyl)-methanesulfonyl chloride (25068-94-4)

Guidance literature:

Na-Salz von o-Iodbenzylsulfonsaeure, PCl5;

DOI:10.1007/BF01199621

Reference yield: 63.0%

methyl 2-aminonicotinate (14667-47-1) + (2-iodo-phenyl)-methanesulfonyl chloride (25068-94-4) → methyl 2-{[(2-iodobenzyl)sulfonyl]amino}nicotinate (1362699-05-5)

Guidance literature:

methyl 2-aminonicotinate; (2-iodo-phenyl)-methanesulfonyl chloride; With pyridine; In dichloromethane; at 20 ℃; for 12h;

With hydrogenchloride; In dichloromethane; water;

Downstream raw materials:

N-allyl-C-(2-iodo-phenyl)-methanesulfonamide

7-(2-iodo-phenyl)-2,3,6,7-tetrahydro-[1,2]thiazepine 1,1-dioxide

1-(2-iodo-phenyl)-but-3-ene-1-sulfonic acid allylamide

methyl 4-{[(2-iodobenzyl)sulfonyl]amino}-1,3-thiazole-5-carboxylate

Refernces

• 1、 Preston, Adam J,Paquette, Leo A.. "Brominative indolization of an unsaturated bridgehead sultam with extrusion of sulfur dioxide". . p. 41 - 44. Retrieved 2007/10/03.