N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide

Base Information

• Chemical Name: N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide
• CAS No.: 908375-20-2
• Molecular Formula: C₁₈H₂₂FN₃O
• Molecular Weight: 315.391
• Mol file: 908375-20-2.mol

Synonyms:N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide

Chemical Property of N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide

There total 2 articles about N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethyl-2-hydroxybutyl)-phenyl]-1H-pyrazole-4-carboxamide → N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide (908375-20-2) + 5-fluoro-1,3-dimethyl-N-[2-(1,3-dimethylbuten-2-yl)phenyl]-1H-pyrazole-4-carboxamide + 5-fluoro-1,3-dimethyl-N-[2-(2-chloro-1,3-dimethylbutyl)phenyl]-1H-pyrazole-4-carboxamide

Guidance literature:

With pyridine; phosphoric acid; trichlorophosphate; for 3h;

Reference yield:

5-fluoro-N-(2-(1-hydroxy-1,3-dimethylbutyl)phenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide (494794-02-4) → N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide (908375-20-2) + 2-(5-fluoro-1,3-dimethyl-1H-pyrazol-4-yl)-4-isobutyl-4-methyl-4H-3,1-benzoxazine (908375-19-9) + 5-fluoro-1,3-dimethyl-N-(2-(3-methyl-1-methylenebutyl)phenyl)-1H-pyrazole-4-carboxamide (908375-21-3)

Guidance literature:

With sulfuric acid; trimethyl orthoformate; In toluene; for 1h; Heating / reflux;

Reference yield: 97.0%

N-(2-((1E/Z)-1,3-dimethylbut-1-en-1-yl)phenyl)-1,3-dimethyl-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide (908375-20-2) → penflufen (494793-67-8)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 40 ℃; for 19h; under 37503.8 Torr; Product distribution / selectivity;

upstream raw materials:

5-fluoro-N-(2-(1-hydroxy-1,3-dimethylbutyl)phenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide

Downstream raw materials:

penflufen

5-fluoro-N-(2-(1-hydroxy-1,3-dimethylbutyl)phenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamide