{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

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Chemical Name:{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine
CAS No.:139153-10-9
Molecular Formula:C₃₁H₄₆N₂O₅
Molecular Weight:526.717
Hs Code.:

Synonyms:{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

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Chemical Property of {(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

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Technology Process of {(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

There total 3 articles about {(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54149-17-6,92450-98-1
2-bromoethyl 2-methoxyethyl ether

: 139153-10-9
{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1) LDA / 1) Et₂O, hexane, 0 deg C, 5 h, 2) -110 deg C, 3 h

2: 1) LDA / 1) Et₂O, hexane, r.t., 5 h, 2) -110 deg C, 3 h

With lithium diisopropyl amide;
DOI:10.1055/s-1991-28405

Reference yield:

: 59983-37-8
(+)-(S)-1-(1-benzyl-phenylethylideneamino)-2-methoxymethyl pyrrolidine

: 139153-10-9
{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1) LDA / 1) Et₂O, hexane, 0 deg C, 5 h, 2) -110 deg C, 3 h

2: 1) LDA / 1) Et₂O, hexane, r.t., 5 h, 2) -110 deg C, 3 h

With lithium diisopropyl amide;
DOI:10.1055/s-1991-28405

Reference yield:

: 54149-17-6,92450-98-1
2-bromoethyl 2-methoxyethyl ether

: 139153-07-4,139176-23-1
[(R)-1-Benzyl-4-(2-methoxy-ethoxy)-2-phenyl-but-(Z)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

: 139153-10-9
{(R)-4-(2-Methoxy-ethoxy)-1-[(R)-3-(2-methoxy-ethoxy)-1-phenyl-propyl]-2-phenyl-butylidene}-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1) Et₂O, hexane, r.t., 5 h, 2) -110 deg C, 3 h;
DOI:10.1055/s-1991-28405