2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

Base Information

Chemical Name:2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde
CAS No.:1096535-78-2
Molecular Formula:C₂₃H₃₅NO₃Si
Molecular Weight:401.621
Hs Code.:

Synonyms:2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

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Technology Process of 2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

There total 1 articles about 2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 1096535-63-5
4-bromo-2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1096535-78-2
2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

Guidance literature:: 4-bromo-2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.025h;

N,N-dimethyl-formamide; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1016/j.bmcl.2008.06.084

Reference yield: 73.0%

: 1096535-78-2
2-(1-(tert-butyldimethylsilyloxy)-7-phenylheptyl)oxazole-4-carboxaldehyde

: 1096535-79-3
2-(1-hydroxy-7-phenylheptyl)oxazole-4-carboxaldehyde

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.bmcl.2008.06.084