tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate
CAS No.:914299-14-2
Molecular Formula:C₁₆H₂₂BrNO₂
Molecular Weight:340.26
Hs Code.:
Mol file:914299-14-2.mol

Synonyms:tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Suppliers and Price of tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
tert-butyl2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate 95
10g
$ 2475.00

Labseeker
tert-butyl2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate 95
5g
$ 1833.00

American Custom Chemicals Corporation
TERT-BUTYL 2-(4-BROMO-2-METHYLPHENYL)PYRROLIDINE-1-CARBOXYLATE 95.00%
5MG
$ 503.67

Total 0 raw suppliers

Chemical Property of tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:: tert-butyl2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

There total 6 articles about tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 2-(4-bromo-2-methylphenyl)pyrrolidine hydrochloride

: 914299-14-2
tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;

Reference yield: 81.0%

: 914299-13-1
2-(4-bromo-2-methylphenyl)pyrrolidine

: 24424-99-5
di-tert-butyl dicarbonate

: 914299-14-2
tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Guidance literature:: With potassium carbonate; In dichloromethane; at 23 ℃; for 12h;
DOI:10.1016/j.bmcl.2008.09.081

Reference yield:

: 914299-12-0
C₁₁H₁₂BrN

: 914299-14-2
tert-butyl 2-(4-bromo-2-methylphenyl)pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol; acetic acid / 2.5 h / -60 - -40 °C

2: potassium carbonate / dichloromethane / 5 - 20 °C

With sodium tetrahydroborate; potassium carbonate; In methanol; dichloromethane; acetic acid;