2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride

Base Information

• Chemical Name: 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride
• CAS No.: 13558-31-1
• Molecular Formula: C20H15ClN2O3
• Molecular Weight: 366.804
• Hs Code.: 29329990
• European Community (EC) Number: 236-944-7
• DSSTox Substance ID: DTXSID90921578
• Wikidata: Q27123374
• Mol file: 13558-31-1.mol

Synonyms:rhodamine 110

Chemical Property of 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride

Chemical Property:

• Appearance/Colour: red to bordeaux crystals or crystalline powder
• Vapor Pressure: 1.06E-16mmHg at 25°C
• Melting Point: >300 °C(lit.)
• Refractive Index: 1.6470 (estimate)
• Boiling Point: 629.3°C at 760 mmHg
• Flash Point: 334.4°C
• PSA: 100.31000
• Density: 1.2504 (rough estimate)
• LogP: 5.44740
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: ethanol: soluble
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 366.0771200
• Heavy Atom Count: 26
• Complexity: 691

Purity/Quality:

99% ^*data from raw suppliers

Rhodamine110 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 22-24/25-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Rhodamine Dyes
• Canonical SMILES: C1=CC=C(C(=C1)C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N)C(=O)O.Cl
• Description: Rhodamine 110 is a green fluorescent cationic dye with excitation and emission maxima of 496 and 520 nm, respectively. When incorporated with a hydrolytic substrate (e.g., proteinase or peptidase substrates), it can be used as a highly sensitive detection reagent in fluorescence-based enzyme assays. Rhodamine 110 has also been used in a fluorescence quenching method for determining trace nitrite and as a probe for cytochrome P450 activity.
• Uses: Rhodamine 110 is a fluorescent dye used as AP- and exopeptidase substrates for flow cytometric measurements. Rhodamine 110 is a fluorescent dye used as AP- and exopeptidase substrates for flow cytometric measurements. Dyes and metabolites.

Technology Process of 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride

There total 11 articles about 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ rhodamine 110 hydrochloride salt (13558-31-1)

Guidance literature:

With triethylamine; In [⁽²⁾H₆]acetone; water;

Reference yield: 91.0%

3,6-diazidoxanthene-9-spiro-1'-isobenzofuran-3'(1'H)-one → rhodamine 110 chloride (13558-31-1)

Guidance literature:

With thiophenol; sodium L-ascorbate; In dimethyl sulfoxide; at 37 ℃; for 1h; pH=7.25; aq. phosphate buffer;

DOI:10.1002/cbic.201100719

Reference yield: 17.0%

phthalic anhydride (85-44-9) + m-Hydroxyaniline (591-27-5) → rhodamine 110 chloride (13558-31-1)

Guidance literature:

With sulfuric acid; at 180 ℃; for 5h;

DOI:10.1002/chem.201803234

upstream raw materials:

rhodamine B

oxygen

phthalic anhydride

m-Hydroxyaniline

Downstream raw materials:

rhodamine 110

Refernces

• 1、 Marucco,Carella,Fenoglio. "A comparative study on the efficacy of different probes to predict the photo-activity of nano-titanium dioxide toward biomolecules". . p. 89559 - 89568. Retrieved 2015.
• 2、 Jahurul Islam,Kim, Hyun Kook,Amaranatha Reddy,Kim, Yujin,Ma, Rory,Baek, Heehyun,Kim, Joonghan,Kim, Tae Kyu. "Hierarchical BiOI nanostructures supported on a metal organic framework as efficient photocatalysts for degradation of organic pollutants in water". . p. 6013 - 6023. Retrieved 2017.
• 3、 Jana,Pal,Chatterjee. "Self assembled flower like CdS-ZnO nanocomposite and its photo catalytic activity". . p. 510 - 515. Retrieved 2014.
• 4、 Hammler, Daniel,Marx, Andreas,Zumbusch, Andreas. "Fluorescence-Lifetime-Sensitive Probes for Monitoring ATP Cleavage". . p. 15329 - 15335. Retrieved 2018.
• 5、 Chronopoulos,Karousis,Zhao,Wang,Shinohara,Tagmatarchis. "Photocatalytic application of nanosized CdS immobilized onto functionalized MWCNTs". . p. 7429 - 7434. Retrieved 2014.
• 6、 Prakash, Natarajan,Thangaraju, Dheivasigamani,Karthikeyan, Rajan,Arivanandhan, Mukannan,Shimura, Yosuke,Hayakawa, Yasuhiro. "UV-visible and near-infrared active NaGdF4:Yb:Er/Ag/TiO2 nanocomposite for enhanced photocatalytic applications". . p. 80655 - 80665. Retrieved 2016.
• 7、 Chen, Lirong,Hao, Xihong,Li, Yong,Lu, Chunxiao,Shi, Lu,Zhang, Qiwei,Zhang, Tiejun. "Piezocatalytic performance of Na0.5Bi0.5TiO3 nanoparticles for degradation of organic pollutants". . . Retrieved 2021/11/16.