(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Base Information

Chemical Name:(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride
CAS No.:1269488-13-2
Molecular Formula:C₂₃H₂₇N₃O₃*ClH
Molecular Weight:429.947
Hs Code.:

Synonyms:(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Suppliers and Price of (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

There total 4 articles about (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: (2S)-N⁴-benzyloxycarbonyl-1,2,4-triaminobutane dihydrochloride

: 196512-99-9
2-ethyl-2,3-dihydro-1-benzofuran-2-carboxylic acid nitrile

: 1269488-13-2
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Guidance literature:: 2-ethyl-2,3-dihydro-1-benzofuran-2-carboxylic acid nitrile; With sodium ethanolate; In ethanol; at 20 ℃;

(2S)-N⁴-benzyloxycarbonyl-1,2,4-triaminobutane dihydrochloride; In ethanol; for 4h; Reflux;
DOI:10.1016/j.bmc.2010.11.039

Reference yield:

: 2-ethyl-2,3-dihydro-1-benzofuran-2-carboxylic acid methyl ester

: 1269488-13-2
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonia / methanol / 48 h / 20 °C

2.1: pyridine; trichlorophosphate / Reflux; Cooling with ice

3.1: sodium ethanolate / ethanol / 20 °C

3.2: 4 h / Reflux

With pyridine; ammonia; sodium ethanolate; trichlorophosphate; In methanol; ethanol;
DOI:10.1016/j.bmc.2010.11.039

Reference yield:

: 170803-36-8
2-ethyl-2,3-dihydro-1-benzofuran-2-carboxylic acidamide

: 1269488-13-2
(4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-(2-ethyl-2,3-dihydro-benzofuran-2-yl)imidazoline hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine; trichlorophosphate / Reflux; Cooling with ice

2.1: sodium ethanolate / ethanol / 20 °C

2.2: 4 h / Reflux

With pyridine; sodium ethanolate; trichlorophosphate; In ethanol;
DOI:10.1016/j.bmc.2010.11.039