C₂₂H₂₉NO₆

Base Information

• Chemical Name: C₂₂H₂₉NO₆
• CAS No.: 1315594-77-4
• Molecular Formula: C₂₂H₂₉NO₆
• Molecular Weight: 403.475
• Mol file: 1315594-77-4.mol

Synonyms:C₂₂H₂₉NO₆

Chemical Property of C₂₂H₂₉NO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₂H₂₉NO₆

There total 2 articles about C₂₂H₂₉NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

C12H22NO8P (1315594-73-0) + (S)-(-)-2-Benzyloxypent-4-enal (87604-58-8) → C22H29NO6 (1315594-77-4)

Guidance literature:

C₁₂H₂₂NO₈P; With caesium carbonate; In acetonitrile; at 20 ℃; for 0.75h; Inert atmosphere;

(S)-(-)-2-Benzyloxypent-4-enal; In acetonitrile; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo2010389

Reference yield:

(4S,5S)-2,2-Dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-(methoxy-methyl-amide) (426826-05-3) → C22H29NO6 (1315594-77-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.67 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 °C / Inert atmosphere

2.1: caesium carbonate / acetonitrile / 0.75 h / 20 °C / Inert atmosphere

2.2: 1 h / 0 °C / Inert atmosphere

With caesium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; acetonitrile; 2.1: Horner-Wadsworth-Emmons olefination / 2.2: Horner-Wadsworth-Emmons olefination;

DOI:10.1021/jo2010389

Reference yield: 74.0%

C22H29NO6 (1315594-77-4) + chloromethyl methyl ether (107-30-2) → C24H36O7 (1315594-87-6) + C24H35NO7 (1315594-85-4)

Guidance literature:

C₂₂H₂₉NO₆; With cerium(III) chloride heptahydrate; In methanol; at 20 ℃; for 0.75h; Inert atmosphere;

With sodium tetrahydroborate; In methanol; at -78 ℃; for 1.08333h; Inert atmosphere;

chloromethyl methyl ether; With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jo2010389

upstream raw materials:

C₁₂H₂₂NO₈P

(S)-(-)-2-Benzyloxypent-4-enal

(4S,5S)-2,2-Dimethyl-[1,3]dioxolane-4,5-dicarboxylic acid bis-(methoxy-methyl-amide)

Downstream raw materials:

C₂₃H₃₄O₆

C₂₉H₄₈O₆Si

C₂₀H₂₈O₅

C₂₂H₃₁NO₆