5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

Base Information

• Chemical Name: 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester
• CAS No.: 121387-61-9
• Molecular Formula: C₂₇H₂₈N₂O₃
• Molecular Weight: 428.531

Synonyms:5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

Chemical Property of 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

There total 4 articles about 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

5-Acetoxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester (121387-58-4) → 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester (121387-61-9)

Guidance literature:

With potassium hydroxide; In ethanol; at 60 ℃; for 1h;

DOI:10.1007/BF00758313

Reference yield:

piperidine (110-89-4) → 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester (121387-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / benzene / 20 h / Ambient temperature

2: 67 percent / KOH / ethanol / 1 h / 60 °C

With potassium hydroxide; In ethanol; benzene;

DOI:10.1007/BF00758313

Reference yield:

1-phenyl-2-bromomethyl-3-ethoxycarbonyl-5-acetoxybenzindole (121387-55-1) → 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester (121387-61-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / benzene / 20 h / Ambient temperature

2: 67 percent / KOH / ethanol / 1 h / 60 °C

With potassium hydroxide; In ethanol; benzene;

DOI:10.1007/BF00758313

upstream raw materials:

5-Acetoxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

piperidine

1-phenyl-2-bromomethyl-3-ethoxycarbonyl-5-acetoxybenzindole

1-phenyl-2-methyl-3-ethoxycarbonyl-5-acetoxybenzindole

Downstream raw materials:

1-phenyl-2,4-dipiperidinomethyl-3-ethoxycarbonyl-5-oxybenzindole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 121387-61-9 5-Hydroxy-1-phenyl-2-piperidin-1-ylmethyl-1H-benzo[g]indole-3-carboxylic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send