methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Base Information

Chemical Name:methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate
CAS No.:946402-88-6
Molecular Formula:C₂₂H₂₈N₄O₂
Molecular Weight:380.49
Hs Code.:

Synonyms:methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Suppliers and Price of methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

There total 2 articles about methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-53-0
3-phenyl-propionaldehyde

: 946403-27-6
C₁₃H₁₈N₄O₂

: 946402-88-6
methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Guidance literature:: 3-phenyl-propionaldehyde; C₁₃H₁₈N₄O₂; With sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h;

With water; sodium hydrogencarbonate; In dichloromethane; for 0.333333h; Product distribution / selectivity;

Reference yield:

: 876162-25-3
methyl (2E)-3-(5-chloro-2-pyrazinyl)acrylate

: 946402-87-5
(3R)-1-(3-phenylpropyl)-3-piperidineamine

: 946402-88-6
methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

Guidance literature:: methyl (2E)-3-(5-chloro-2-pyrazinyl)acrylate; (3R)-1-(3-phenylpropyl)-3-piperidineamine; With potassium phosphate; In N,N-dimethyl acetamide; at 90 - 95 ℃; for 2h;

With hydrogenchloride; In N,N-dimethyl acetamide; water; pH=8.0; Product distribution / selectivity;

Reference yield:

: 946402-88-6
methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate

: 946402-89-7
(2E)-3-[5-((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino-2-pyrazinyl]acrylic acid

Guidance literature:: methyl (2E)-3-[5-[((3R)-1-(3-phenylpropyl)-3-piperidinyl)amino]-2-pyrazinyl]acrylate; With methanol; sodium hydroxide; water; at 50 - 55 ℃; for 3h;

With hydrogenchloride; In methanol; water;