C₂₈H₂₇N₃O₂

Base Information

Chemical Name:C₂₈H₂₇N₃O₂
CAS No.:468751-17-9
Molecular Formula:C₂₈H₂₇N₃O₂
Molecular Weight:437.541
Hs Code.:

C<sub>28</sub>H<sub>27</sub>N<sub>3</sub>O<sub>2</sub>

Synonyms:C₂₈H₂₇N₃O₂

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Chemical Property of C₂₈H₂₇N₃O₂

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Technology Process of C₂₈H₂₇N₃O₂

There total 6 articles about C₂₈H₂₇N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 468751-15-7
C₃₁H₃₅N₃O₂Si

: 468751-17-9
C₂₈H₂₇N₃O₂

Guidance literature:: With potassium hydroxide; In methanol;
DOI:10.1016/S0040-4039(02)00539-7

Reference yield:

: 626-01-7
3-Iodoaniline

: 468751-17-9
C₂₈H₂₇N₃O₂

Guidance literature:: Multi-step reaction with 7 steps

1.1: 6M HCl; NaNO₂

1.2: K₂CO₃ / acetonitrile; H₂O

2.1: pyrrolidine / Pd(Ph₃P)4; CuI

3.1: 85 percent / KOH; 18-crown-6 / tetrahydrofuran

4.1: nBuLi / tetrahydrofuran

5.1: I₂; MeI

6.1: 80.1 percent / Ph₃P / Pd(dba)2; CuI / triethylamine

7.1: 100 percent / 1M KOH / methanol

With pyrrolidine; hydrogenchloride; potassium hydroxide; n-butyllithium; 18-crown-6 ether; iodine; triphenylphosphine; sodium nitrite; methyl iodide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; methanol; triethylamine; 6.1: Sonogashira coupling;
DOI:10.1016/S0040-4039(02)00539-7

Reference yield:

: 468751-09-9
C₁₃H₁₇N₃O

: 468751-17-9
C₂₈H₂₇N₃O₂

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / KOH; 18-crown-6 / tetrahydrofuran

2: nBuLi / tetrahydrofuran

3: I₂; MeI

4: 80.1 percent / Ph₃P / Pd(dba)2; CuI / triethylamine

5: 100 percent / 1M KOH / methanol

With potassium hydroxide; n-butyllithium; 18-crown-6 ether; iodine; triphenylphosphine; methyl iodide; copper(l) iodide; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; methanol; triethylamine; 4: Sonogashira coupling;
DOI:10.1016/S0040-4039(02)00539-7