dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate

Base Information

• Chemical Name: dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate
• CAS No.: 1138088-04-6
• Molecular Formula: C₃₇H₄₈N₄O₉S
• Molecular Weight: 724.876
• Mol file: 1138088-04-6.mol

Synonyms:dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate

Chemical Property of dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate

There total 1 articles about dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dioxopyrrolidin-1-yl N-(methoxycarbonyl)-β-phenyl-L-phenylalaninate (938193-51-2) + dimethyl 2-amino-6-((4-aminophenylsulfonyl)(3-methylbutyl)amino)heptanedioate (1138088-01-3) → dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate (1138088-04-6)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; water; acetone; at 20 ℃; for 16h;

Reference yield:

dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate (1138088-04-6) → N-(5-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-hydroxy-1-hydroxymethylhexyl)-Nα-methoxycarbonyl-β-phenyl-L-phenylalaninamide

Guidance literature:

dimethyl 2-((4-aminophenylsulfonyl)(3.methylbutyl)amino)-6-(N-methoxycarbonyl-β-phenyl-L-phenylalanylamino)heptanedioate; With lithium borohydride; In tetrahydrofuran; for 0.5h;

With methanol; In tetrahydrofuran; for 1h;

upstream raw materials:

2,5-dioxopyrrolidin-1-yl N-(methoxycarbonyl)-β-phenyl-L-phenylalaninate

dimethyl 2-amino-6-((4-aminophenylsulfonyl)(3-methylbutyl)amino)heptanedioate