2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone

Base Information

• Chemical Name: 2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone
• CAS No.: 89358-96-3
• Molecular Formula: C₁₄H₁₈O₅
• Molecular Weight: 266.294
• Mol file: 89358-96-3.mol

Synonyms:2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone

Chemical Property of 2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone

There total 1 articles about 2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl 2,3-dideoxy-4,5:6,7-di-O-isopropylidene-3C-(p-tolyl)-D-manno-heptonate (89358-86-1) → 2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone (89358-96-3)

Guidance literature:

With hydrogenchloride; In ethanol;

DOI:10.1039/P19830002629

Reference yield:

2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone (89358-96-3) → (+)-(S)-3-(4-methylphenyl)butyro-1,4-lactone (89359-17-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) aq. sodium hydroxide, aq. potassium dihydrogen phosphate (pH 6.5), 2.) sodium metaperiodate

2: 87 percent / sodium borohydride / methanol

With sodium hydroxide; sodium tetrahydroborate; sodium periodate; potassium dihydrogenphosphate; In methanol;

DOI:10.1039/P19830002629

Reference yield:

2,3-dideoxy-3C-(4-methylphenyl)-D-manno-heptono-1,4-lactone (89358-96-3) → (+)-(S)-2-(p-tolyl)butane-1,4-dioic acid (89359-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) aq. sodium hydroxide, aq. potassium dihydrogen phosphate (pH 6.5), 2.) sodium metaperiodate

2: 55 percent / chromium trioxide, sulphuric acid / H₂O; acetone

With chromium(VI) oxide; sodium hydroxide; sodium periodate; potassium dihydrogenphosphate; sulfuric acid; In water; acetone;

DOI:10.1039/P19830002629

upstream raw materials:

ethyl 2,3-dideoxy-4,5:6,7-di-O-isopropylidene-3C-(p-tolyl)-D-manno-heptonate

Downstream raw materials:

4-hydroxy-3-(p-tolyl)butyro-1,4-lactone

(+)-(S)-3-(4-methylphenyl)butyro-1,4-lactone

(+)-(S)-2-(p-tolyl)butane-1,4-dioic acid