Technology Process of C16H16N2O3
There total 6 articles about C16H16N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; acetic acid;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
DOI:10.1016/j.bmcl.2015.12.090
- Guidance literature:
-
Multi-step reaction with 6 steps
1: triethylamine / N,N-dimethyl-formamide / 24 h / 20 °C / Inert atmosphere
2: sodium hydroxide / water; ethanol / 3 h
3: 1H-imidazole / N,N-dimethyl-formamide / 5 h / 20 °C / Inert atmosphere
4: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C
5: pyridine / 16 h / 20 °C
6: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 24 h / 20 °C
With
pyridine; 1H-imidazole; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; hydrogen; acetic acid; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2015.12.090
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1H-imidazole / N,N-dimethyl-formamide / 5 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C
3: pyridine / 16 h / 20 °C
4: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 24 h / 20 °C
With
pyridine; 1H-imidazole; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; hydrogen; acetic acid;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2015.12.090
