N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide
CAS No.:562039-10-5
Molecular Formula:C₁₉H₂₃F₃N₂O₄
Molecular Weight:400.398
Hs Code.:

Synonyms:N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

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Technology Process of N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

There total 2 articles about N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14815-12-4
N-(2-methoxyphenyl)-2,2,2-trifluoro-acetamide

: 142853-09-6
3-(1-acetyl-4-piperidinyl)propionyl chloride

: 562039-10-5
N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

Guidance literature:: aluminum (III) chloride; at 20 ℃; for 1h;

Reference yield:

: 131417-49-7
3-[1-(acetyl)-4-piperidinyl]propionic acid

: 562039-10-5
N-{5-[3-(1-acetyl-4-piperidinyl)propanoyl]-2-methoxyphenyl}-2,2,2-trifluoroacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / dichloromethane / 0.5 h / 0 °C

2: aluminum (III) chloride / 1 h / 20 °C

With thionyl chloride; aluminum (III) chloride; In dichloromethane;