phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate

Base Information

• Chemical Name: phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate
• CAS No.: 301832-44-0
• Molecular Formula: C₂₂H₂₅NO₂S
• Molecular Weight: 367.512
• Mol file: 301832-44-0.mol

Synonyms:phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate

Chemical Property of phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate

There total 3 articles about phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) + (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)amine → phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate (301832-44-0)

Guidance literature:

With triethylamine; In benzene; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(00)00579-2

Reference yield:

(E)-3-Methyl-4-(thiophenoxy)-2-buten-1-ol (78592-86-6) → phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate (301832-44-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.6 g / CBr₄; Ph₃P / benzene / 2 h / 0 °C

2: CH₂Cl₂ / 4 h / 20 °C

3: 700 mg / Et₃N / benzene / 2 h / 20 °C

With carbon tetrabromide; triethylamine; triphenylphosphine; In dichloromethane; benzene; 1: Substitution / 2: Substitution / 3: Acylation;

DOI:10.1016/S0040-4020(00)00579-2

Reference yield:

(E)-1-bromo-3-methyl-4-(phenylsulfanyl)-2-butene (301832-48-4) → phenylmethyl (E)-N-[3-methyl-4-(phenylsulfanyl)-2-butenyl] (2-propenyl)carbamate (301832-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂ / 4 h / 20 °C

2: 700 mg / Et₃N / benzene / 2 h / 20 °C

With triethylamine; In dichloromethane; benzene; 1: Substitution / 2: Acylation;

DOI:10.1016/S0040-4020(00)00579-2

upstream raw materials:

benzyl chloroformate

(E)-3-Methyl-4-(thiophenoxy)-2-buten-1-ol

(E)-1-bromo-3-methyl-4-(phenylsulfanyl)-2-butene