(acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate

Base Information

• Chemical Name: (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate
• CAS No.: 162380-34-9
• Molecular Formula: C₃₅H₅₂O₅Si
• Molecular Weight: 580.88
• Mol file: 162380-34-9.mol

Synonyms:(acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate

Chemical Property of (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate

There total 4 articles about (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.2%

4-hydroxybutyl acrylate (2478-10-6,29086-87-1) + 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoic acid (162380-33-8) → (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate (162380-34-9)

Guidance literature:

With bis-2-propyl carbonate; 4-(dimethylamino)pyridinium tosylate; In dichloromethane; for 25h;

DOI:10.1021/ja00124a005

Reference yield:

p-Toluic acid (99-94-5) → (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate (162380-34-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) potassium tert-butoxide, LDA / 1.) THF, hexane, -78 deg C, 4 h, 2.) THF, hexane, from -78 deg C to 0 deg C, 2.5 h

2: 88.2 percent / DPTS, DIPC / CH₂Cl₂ / 25 h

With bis-2-propyl carbonate; potassium tert-butylate; 4-(dimethylamino)pyridinium tosylate; lithium diisopropyl amide; In dichloromethane;

DOI:10.1021/ja00124a005

Reference yield:

6-{4-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-phenyl}-hexan-1-ol (162380-31-6) → (acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate (162380-34-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 83.3 percent / CBr₄, PPh₃ / acetonitrile / 2 h / Ambient temperature

2: 1.) potassium tert-butoxide, LDA / 1.) THF, hexane, -78 deg C, 4 h, 2.) THF, hexane, from -78 deg C to 0 deg C, 2.5 h

3: 88.2 percent / DPTS, DIPC / CH₂Cl₂ / 25 h

With carbon tetrabromide; bis-2-propyl carbonate; potassium tert-butylate; triphenylphosphine; 4-(dimethylamino)pyridinium tosylate; lithium diisopropyl amide; In dichloromethane; acetonitrile;

DOI:10.1021/ja00124a005

upstream raw materials:

4-hydroxybutyl acrylate

4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoic acid

p-Toluic acid

6-{4-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-phenyl}-hexan-1-ol

Downstream raw materials:

(acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate