ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Base Information

Chemical Name:ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate
CAS No.:131105-69-6
Molecular Formula:C₂₂H₁₆BrF₆N₃O₃S
Molecular Weight:596.348
Hs Code.:

Synonyms:ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Suppliers and Price of ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

There total 3 articles about ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 131105-68-5
ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-oxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

: 131105-69-6
ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Guidance literature:: With tetraphosphorus decasulfide; In benzene; at 70 ℃; for 4h;
DOI:10.1021/jm00105a018

Reference yield:

: 131105-67-4
2'-bromo-3',5'-bis(trifluoromethyl)-2-chloroacetanilide

: 131105-69-6
ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / t-BuOK / dimethylformamide / 0.5 h / Ambient temperature

2: 59 percent / P₄S₁₀ / benzene / 4 h / 70 °C

With tetraphosphorus decasulfide; potassium tert-butylate; In N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00105a018

Reference yield:

: 25947-13-1
ethyl 1,2-dihydro-1-oxophthalazin-4-ylacetate

: 131105-69-6
ethyl 3-<2-<<2-bromo-3,5-bis(trifluoromethyl)phenyl>amino>-2-thioxoethyl>-3,4-dihydro-4-oxo-1-phthalazineacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / t-BuOK / dimethylformamide / 0.5 h / Ambient temperature

2: 59 percent / P₄S₁₀ / benzene / 4 h / 70 °C

With tetraphosphorus decasulfide; potassium tert-butylate; In N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00105a018