(1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane

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Chemical Name:(1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane
CAS No.:291775-65-0
Molecular Formula:C₁₈H₃₀N₂O₄
Molecular Weight:338.447
Hs Code.:

Synonyms:(1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane

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Chemical Property of (1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane

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Technology Process of (1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane

There total 1 articles about (1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 63126-47-6
(2S)-2-(methoxymethyl)-1-pyrrolidine

: 291775-53-6,134795-25-8,291775-59-2,134877-63-7
(1S,3R,4R)-N-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

: 291775-65-0
(1S,3R,4R)-N-tert-butoxycarbonyl-3-[N-((2S)-2-methoxymethyl)pyrrolidinyl]carbonyl-2-azabicyclo[2.2.1]heptane

Guidance literature:: (1S,3R,4R)-N-tert-butoxycarbonyl-2-azabicyclo[2.2.1]heptane-3-carboxylic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; at 0 ℃; for 0.25h;

(2S)-2-(methoxymethyl)-1-pyrrolidine; In dichloromethane; at 20 ℃; Further stages.;
DOI:10.1021/ja000545t