Zelandopam hydrochloride

Base Information

Chemical Name:Zelandopam hydrochloride
CAS No.:138086-00-7
Molecular Formula:C₁₅H₁₅NO₄*ClH
Molecular Weight:309.749
Hs Code.:
UNII:99I770UEI4
Wikidata:Q27272215
Mol file:138086-00-7.mol

Synonyms:(-)-(S)-4-(3,4-dihydroxyphenyl)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline;7,8-DDPTI;7,8-dihydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline;YM 435;YM-435;YM435;zelandopam

Suppliers and Price of Zelandopam hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Zelandopam hydrochloride

Chemical Property:

Vapor Pressure:2.66E-20mmHg at 25°C
Boiling Point:695.4°Cat760mmHg
Flash Point:374.4°C
PSA：92.95000
Density:g/cm³
LogP:2.87490
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:309.0767857
Heavy Atom Count:21
Complexity:340

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C2=C(CN1)C(=C(C=C2)O)O)C3=CC(=C(C=C3)O)O.Cl
Isomeric SMILES:C1[C@H](C2=C(CN1)C(=C(C=C2)O)O)C3=CC(=C(C=C3)O)O.Cl

Technology Process of Zelandopam hydrochloride

There total 6 articles about Zelandopam hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 138085-97-9
1-[(R)-4-(3,4-Dihydroxy-phenyl)-7,8-dihydroxy-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone

: 138086-00-7
(R)-(+)-7,8-dihydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 43h; Heating;
DOI:10.1248/cpb.39.2910

Reference yield:

: 138085-98-0
1-[(S)-4-(3,4-Dihydroxy-phenyl)-7,8-dihydroxy-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone

: 138086-00-7
Zelandopam hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 43h; Heating;
DOI:10.1248/cpb.39.2910

Reference yield:

: (-)-7,8-dimethoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

: 138086-00-7
Zelandopam hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 31.9 g / CH₂Cl₂ / 0.17 h / Ambient temperature

2: 25.2 g / BBr₃ / CH₂Cl₂ / 1.5 h / Ambient temperature

3: 75.4 g / 3 N HCl / ethanol / 43 h / Heating

With hydrogenchloride; boron tribromide; In ethanol; dichloromethane;
DOI:10.1248/cpb.39.2910