5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

Base Information

Chemical Name:5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid
CAS No.:1120330-33-7
Molecular Formula:C₂₃H₂₉NO₅S
Molecular Weight:431.553
Hs Code.:

Synonyms:5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

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Chemical Property of 5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

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Technology Process of 5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

There total 6 articles about 5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1008516-27-5
C₂₄H₃₁NO₅S

: 1120330-33-7
5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

Guidance literature:: Rabbit liver esterase; In water; acetonitrile; at 20 ℃; for 144h; pH=7.2;

Reference yield:

: C₃₀H₄₅NO₅SSi

: 1120330-33-7
5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine hydrogenfluoride / acetonitrile / 1.75 h / 0 - 20 °C

2: hexane; ethyl acetate

3: Rabbit liver esterase / water; acetonitrile / 144 h / 20 °C / pH 7.2

With pyridine hydrogenfluoride; Rabbit liver esterase; In hexane; water; ethyl acetate; acetonitrile;

Reference yield:

: 76865-51-5
methyl 5-(4-oxobutyl)thiophene-2-carboxylate

: 1120330-33-7
5-(3-((S)-3-(4-((S)-1-hydroxyhexyl)phenyl)-4-oxooxazolidin-2-yl)propyl)thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: toluene-4-sulfonic acid / toluene / 2 h / Heating / reflux

2: potassium carbonate / copper(l) iodide; N,N`-dimethylethylenediamine / acetonitrile / 96 h / Heating / reflux

3: pyridine hydrogenfluoride / acetonitrile / 1.75 h / 0 - 20 °C

4: hexane; ethyl acetate

5: Rabbit liver esterase / water; acetonitrile / 144 h / 20 °C / pH 7.2

With potassium carbonate; toluene-4-sulfonic acid; pyridine hydrogenfluoride; copper(l) iodide; Rabbit liver esterase; N,N`-dimethylethylenediamine; In hexane; water; ethyl acetate; toluene; acetonitrile;