2-(4-chloro-phenylethynyl)-quinoxaline

Base Information

• Chemical Name: 2-(4-chloro-phenylethynyl)-quinoxaline
• CAS No.: 335159-65-4
• Molecular Formula: C₁₆H₉ClN₂
• Molecular Weight: 264.714
• Mol file: 335159-65-4.mol

Synonyms:2-(4-chloro-phenylethynyl)-quinoxaline

Chemical Property of 2-(4-chloro-phenylethynyl)-quinoxaline

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(4-chloro-phenylethynyl)-quinoxaline

There total 1 articles about 2-(4-chloro-phenylethynyl)-quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-n-chlorophenylacetylene (873-73-4) + 2-iodoquinoxaline (36856-92-5) → 2-(4-chloro-phenylethynyl)-quinoxaline (335159-65-4)

Guidance literature:

With triethylamine; copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; Heating;

DOI:10.1039/b008459j

Reference yield: 89.0%

2-(4-chloro-phenylethynyl)-quinoxaline (335159-65-4) → 2-[(E)-1,2-Dibromo-2-(4-chloro-phenyl)-vinyl]-quinoxaline (335159-78-9)

Guidance literature:

With bromine; In dichloromethane; at 20 ℃;

DOI:10.1039/b008459j

Reference yield:

2-(4-chloro-phenylethynyl)-quinoxaline (335159-65-4) → 2-(4-chloro-phenyl)-thieno[2,3-b]quinoxaline

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / Br₂ / CH₂Cl₂ / 20 °C

2: 80 percent / aq. Na₂CS₃ / methanol / 20 °C

With bromine; sodium trithiocarbonate; In methanol; dichloromethane;

DOI:10.1039/b008459j

upstream raw materials:

4-n-chlorophenylacetylene

2-iodoquinoxaline

Downstream raw materials:

2-[(E)-1,2-Dibromo-2-(4-chloro-phenyl)-vinyl]-quinoxaline

Refernces