2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride

Base Information

Chemical Name:2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride
CAS No.:5832-55-3
Molecular Formula:C8H15 N O3 . Cl H
Molecular Weight:209.673
Hs Code.:2933990090
European Community (EC) Number:227-414-6
NSC Number:281672
Mol file:5832-55-3.mol

Synonyms:5832-55-3;2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride;2-(hydroxymethyl)-1-azabicyclo[2.2.2]octane-3,3-diol;hydrochloride;EINECS 227-414-6;2-Hydroxymethyl-3,3-dihydroxyquinuclidine hydrochloride;2-(hydroxymethyl)-1-azabicyclo[2.2.2]octane-3,3-diol hydrochloride;NSC281672;NSC 281672;NSC-281672;2-(Hydroxymethyl)quinuclidine-3,3-diolhydrochloride

Suppliers and Price of 2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-Methylene-3-quinuclidinone hydrochloride hydrate 96%
5 g
$ 122.00

Total 8 raw suppliers

Chemical Property of 2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride

Chemical Property:

Vapor Pressure:4.1E-06mmHg at 25°C
Melting Point:263 °C (dec.)(lit.)
Boiling Point:344.7°Cat760mmHg
Flash Point:201.9°C
PSA：38.77000
Density:1.39g/cm³
LogP:1.40610
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:209.0818711
Heavy Atom Count:13
Complexity:175

Purity/Quality:

98%min ^*data from raw suppliers

2-Methylene-3-quinuclidinone hydrochloride hydrate 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1C(C2CO)(O)O.Cl

Technology Process of 2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride

There total 1 articles about 2-(Hydroxymethyl)quinuclidine-3,3-diol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5832-55-3
2-Hydroxymethyl-3,3-dihydroxyquinuclidine hydrochloride

Guidance literature:: 2-Methylen-chinuclidinon-(3), aequiv. konz. HCl, A.;

Reference yield:

: 5832-55-3
2-Hydroxymethyl-3,3-dihydroxyquinuclidine hydrochloride

: α-<4-chloro-3-<(methylsulfonyl)amino>benzoyl>-3-oxo-1-azabicyclo<2.2.2>octane-2-propanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / potassium carbonate / H₂O; CH₂Cl₂

2: acetone / Heating

With potassium carbonate; In dichloromethane; water; acetone;
DOI:10.1021/jm00395a014

Reference yield:

: 5832-55-3
2-Hydroxymethyl-3,3-dihydroxyquinuclidine hydrochloride

: 2-<(1-azabicyclo<2.2.2>oct-2-yl)methyl>-1-phenyl-1,3-butanedione

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / potassium carbonate / H₂O; CH₂Cl₂

2: acetone / 24 h / Heating

With potassium carbonate; In dichloromethane; water; acetone;
DOI:10.1021/jm00395a014