7-acetyloxymethyl-6-mercaptopurine

Base Information

• Chemical Name: 7-acetyloxymethyl-6-mercaptopurine
• CAS No.: 119346-80-4
• Molecular Formula: C₈H₈N₄O₂S
• Molecular Weight: 224.243
• Mol file: 119346-80-4.mol

Synonyms:7-acetyloxymethyl-6-mercaptopurine

Chemical Property of 7-acetyloxymethyl-6-mercaptopurine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 7-acetyloxymethyl-6-mercaptopurine

There total 2 articles about 7-acetyloxymethyl-6-mercaptopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) + 7-(dimethylamino)methyl-6-mercaptopurine (119056-59-6) → 6H-purine-6-thione (50-44-2) + 7-acetyloxymethyl-6-mercaptopurine (119346-80-4) + 9-acetyloxymethyl-6-mercaptopurine (114208-88-7) + S6,3-bisacetyloxymethyl-6-mercaptopurine (111621-56-8)

Guidance literature:

With sodium acetate; In dimethylsulfoxide-d6; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1002/jhet.5570250406

Reference yield:

acetic anhydride (108-24-7) + 1,7-di(dipropylamino)methyl-6-mercaptopurine (119346-79-1) → N,N-dipropylacetamide (1116-24-1) + 7-acetyloxymethyl-6-mercaptopurine (119346-80-4)

Guidance literature:

With sodium acetate; In dimethylsulfoxide-d6; Yield given. Further byproducts given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1002/jhet.5570250406

upstream raw materials:

acetic anhydride

7-(dimethylamino)methyl-6-mercaptopurine

1,7-di(dipropylamino)methyl-6-mercaptopurine

Refernces