(S,S)-2-(4-isobutylphenyl)propionic anhydride

Base Information

• Chemical Name: (S,S)-2-(4-isobutylphenyl)propionic anhydride
• CAS No.: 163158-04-1
• Molecular Formula: C₂₆H₃₄O₃
• Molecular Weight: 394.554
• Mol file: 163158-04-1.mol

Synonyms:(S,S)-2-(4-isobutylphenyl)propionic anhydride

Chemical Property of (S,S)-2-(4-isobutylphenyl)propionic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S,S)-2-(4-isobutylphenyl)propionic anhydride

There total 1 articles about (S,S)-2-(4-isobutylphenyl)propionic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(S)-ibuprofen (51146-56-6,58560-75-1) → (S,S)-2-(4-isobutylphenyl)propionic anhydride (163158-04-1)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 2h; optical yield given as %ee; stereospecific reaction;

DOI:10.1016/j.tetasy.2009.02.051

Reference yield: 96.0%

(S,S)-2-(4-isobutylphenyl)propionic anhydride (163158-04-1) → (S)-ibuprofen (51146-56-6,58560-75-1)

Guidance literature:

With lithium hydroxide; water; dihydrogen peroxide; In tetrahydrofuran;

DOI:10.1016/j.tetasy.2009.02.051

Reference yield:

(S,S)-2-(4-isobutylphenyl)propionic anhydride (163158-04-1) + cis,cis,trans-[Pt(NH3)2Cl2(4-phenylbutyrate)(OH)] → C23H34Cl2N2O4Pt

Guidance literature:

In acetonitrile;

DOI:10.1039/c8sc00428e

upstream raw materials:

(S)-ibuprofen

Downstream raw materials:

(S)-ibuprofen