C₃₁H₄₃NO₃

Base Information

• Chemical Name: C₃₁H₄₃NO₃
• CAS No.: 1037302-71-8
• Molecular Formula: C₃₁H₄₃NO₃
• Molecular Weight: 477.687
• Mol file: 1037302-71-8.mol

Synonyms:C₃₁H₄₃NO₃

Chemical Property of C₃₁H₄₃NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₃₁H₄₃NO₃

There total 1 articles about C₃₁H₄₃NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-benzyl-2(R)-methoxy-10-bornylamine (1037302-64-9) + tert-butyl cinnamate (14990-09-1) → C31H43NO3 (1037302-73-0) + C31H43NO3 (1037302-71-8)

Guidance literature:

N-benzyl-2(R)-methoxy-10-bornylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃;

tert-butyl cinnamate; In tetrahydrofuran; hexane; for 1h;

With water; sodium hydrogencarbonate; In tetrahydrofuran; hexane; diastereoselective reaction; Saturated solution;

DOI:10.1021/ol8007793

Reference yield: 76.0%

C31H43NO3 (1037302-71-8) → 2-methoxy-d-bornyl aldehyde (1037303-05-1) + (S)-3-amino-3-phenylpropionic acid tert-butyl ester (120686-18-2)

Guidance literature:

C₃₁H₄₃NO₃; With N-iodo-succinimide; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

With water; sodium hydrogencarbonate; sodium thiosulfate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol8007793

upstream raw materials:

N-benzyl-2(R)-methoxy-10-bornylamine

tert-butyl cinnamate

Downstream raw materials:

2-methoxy-d-bornyl aldehyde

(S)-3-amino-3-phenylpropionic acid tert-butyl ester