N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

Base Information

Chemical Name:N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride
CAS No.:1286174-12-6
Molecular Formula:C₂₂H₂₈ClN₃O₃*ClH
Molecular Weight:454.397
Hs Code.:

Synonyms:N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

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Chemical Property of N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

There total 3 articles about N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1286174-09-1
tert-butyl 2-((2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethyl)(methyl)amino)ethylcarbamate

: 1286174-12-6
N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;

Reference yield:

: 263162-13-6
tert-butyl N-[2-[(2-aminoethyl)(methyl)amino]ethyl]carbamate

: 1286174-12-6
N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 18 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; acetonitrile;

Reference yield:

: 4097-88-5
1,5-diamino-3-azamethylpentane

: 1286174-12-6
N-(2-((2-aminoethyl)(methyl)amino)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 2.75 h / 0 - 20 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 18 h / 20 °C

3: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane; acetonitrile;