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1,2,3,4-Tetrahydro-4-[2-(1-carboxy-3-carbamoylpropylimino)ethylidene]-2,6-pyridinedicarboxylic acid

Base Information
  • Chemical Name:1,2,3,4-Tetrahydro-4-[2-(1-carboxy-3-carbamoylpropylimino)ethylidene]-2,6-pyridinedicarboxylic acid
  • CAS No.:904-62-1
  • Molecular Formula:C14H17N3O7
  • Molecular Weight:339.3007
  • Hs Code.:
  • Mol file:904-62-1.mol
1,2,3,4-Tetrahydro-4-[2-(1-carboxy-3-carbamoylpropylimino)ethylidene]-2,6-pyridinedicarboxylic acid

Synonyms:Vulgaxanthin-I;

Suppliers and Price of 1,2,3,4-Tetrahydro-4-[2-(1-carboxy-3-carbamoylpropylimino)ethylidene]-2,6-pyridinedicarboxylic acid
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The product has achieved commercial mass production*data from LookChem market partment
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Total 5 raw suppliers
Chemical Property of 1,2,3,4-Tetrahydro-4-[2-(1-carboxy-3-carbamoylpropylimino)ethylidene]-2,6-pyridinedicarboxylic acid
Chemical Property:
  • Vapor Pressure:4.35E-27mmHg at 25°C 
  • Boiling Point:785.9°Cat760mmHg 
  • Flash Point:429.1°C 
  • PSA:180.37000 
  • Density:1.56g/cm3 
  • LogP:0.09350 
Purity/Quality:

99% *data from raw suppliers

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SDS file from LookChem

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Refernces

Facile synthesis of α,α′ disubstituted N-hydroxypyrrolidines and N-hydroxypiperidines via double 1,4-addition of hydroxylamine

10.1016/j.tetlet.2006.03.064

The research presents a versatile and efficient method for synthesizing α,α'-disubstituted N-hydroxypiperidines and N-hydroxypyrrolidines through a double 1,4-addition of hydroxylamine to bis α,β-unsaturated diesters. The synthesis occurs in an environmentally friendly ethanol/water system at room temperature. Key chemicals involved include octa-2,6-dienedioic acid diethyl ester and nona-2,6-dienedioic acid diethyl ester, which are synthesized from succinaldehyde or glutaraldehyde. Hydroxylamine is used for the double 1,4-addition, yielding N-hydroxypyrrolidines and N-hydroxypiperidines with good selectivity for the cis isomers. The study also explores the behavior of the double 1,4-addition in systems containing a ketone, revealing that the keto group can be selectively converted to either an oxime or an N-hydroxy compound by adjusting the amount of hydroxylamine.

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