Technology Process of C23H25N3
There total 5 articles about C23H25N3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-benzyl-4-(4-bromo-phenyl)-4-methyl-piperidine;
With
potassium acetate; bis(pinacol)diborane;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride;
In
dimethyl sulfoxide;
at 20 - 100 ℃;
for 2h;
2-bromopyrimidine;
With
potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
water; dimethyl sulfoxide;
at 20 - 100 ℃;
for 2h;
- Guidance literature:
-
With
potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
dimethyl sulfoxide;
at 100 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / 168 h / 100 °C
1.2: pH 7
2.1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 2 h / 100 °C
3.1: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / dimethyl sulfoxide / 2 h / 100 °C
With
aluminum (III) chloride; potassium acetate; potassium carbonate;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium(0);
In
dimethyl sulfoxide;
2.1: Suzuki Coupling / 3.1: Suzuki Coupling;