17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate

Base Information

• Chemical Name: 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate
• CAS No.: 76920-40-6
• Molecular Formula: C₂₆H₃₂O₃Se
• Molecular Weight: 471.498
• Mol file: 76920-40-6.mol

Synonyms:17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate

Chemical Property of 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate

There total 2 articles about 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dehydroepiandrosterone (53-43-0) → 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate (76920-40-6)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; toluene / 0.5 h / Ambient temperature

2: pyridine / tetrahydrofuran; toluene; benzene / 0.5 h / Ambient temperature

With pyridine; In tetrahydrofuran; toluene; benzene;

DOI:10.1002/hlca.19800630823

Reference yield:

3β-chlorocarbonyloxy-androst-5-en-17-one (4913-84-2) + Benzeneselenol (645-96-5) → 17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate (76920-40-6)

Guidance literature:

With pyridine; In tetrahydrofuran; toluene; benzene; for 0.5h; Yield given; Ambient temperature;

DOI:10.1002/hlca.19800630823

Reference yield: 28.0%

17-oxo-androst-5-en-3β-yl Se-phenyl selenocarbonate (76920-40-6) → dehydroepiandrosterone (53-43-0) + 3β-formyl-oxy-5-androsten-17-one (29163-23-3) + 5-androsten-17-one (25824-80-0)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃;

DOI:10.1002/hlca.19800630823

upstream raw materials:

3β-chlorocarbonyloxy-androst-5-en-17-one

Benzeneselenol

dehydroepiandrosterone

Downstream raw materials:

dehydroepiandrosterone

3β-formyl-oxy-5-androsten-17-one

5-androsten-17-one