(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Base Information

Chemical Name:(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate
CAS No.:235786-93-3
Molecular Formula:C₁₇H₁₉NO₂
Molecular Weight:269.343
Hs Code.:

Synonyms:(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Suppliers and Price of (S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of (S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

There total 4 articles about (S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1021452-40-3
(S)-methyl 2-(N-allyl-N-((S)-1-phenylethyl)amino)-2-phenylacetate

: 235786-93-3
(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Guidance literature:: With 1,3-dimethylbarbituric acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; for 3h; Heating;
DOI:10.1002/anie.200704689

Reference yield:

: 1163726-15-5
C₁₇H₁₇NO₂

: methyl 2-phenyl-2-(1-phenylethylamino)acetate

: 235786-93-3
(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Guidance literature:: With C₁₆H₁₇ClN₂O₂; trichlorosilane; In dichloromethane; at 0 ℃; for 12h; diastereoselective reaction; Inert atmosphere;
DOI:10.1021/ol900945h

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 235786-93-3
(S)-methyl 2-((S)-1-phenylethylamino)-2-phenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: MgSO₄ / CH₂Cl₂ / Ambient temperature

2: 1.) Zn, 2.) CuCN(LiCl)2, 3.) BF₃*Et₂O / 1.) THF, 2.) THF, 3.) -78 deg C to room temperature

With boron trifluoride diethyl etherate; magnesium sulfate; zinc; In dichloromethane;
DOI:10.1016/S0040-4020(99)00418-4