N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

Base Information

Chemical Name:N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide
CAS No.:1381785-71-2
Molecular Formula:C₁₆H₁₄F₃N₃O₂S
Molecular Weight:369.367
Hs Code.:

Synonyms:N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

Chemical Property:

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Technology Process of N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

There total 4 articles about N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1381785-70-1
N-(tert-Butoxycarbonyl)-N-(3-ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

: 1381785-71-2
N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;

Reference yield:

: 1381785-69-8
tert-Butyl (3-ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)carbamate

: 1381785-71-2
N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 20 °C

1.2: 20 °C

2.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

With sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1381785-68-7
C₁₁H₉F₃N₂O₂

: 1381785-71-2
N-(3-Ethyl-8-trifluoromethylimidazo[1,2-a]pyridin-2-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; diphenylphosphoranyl azide / 7 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 20 °C

2.2: 20 °C

3.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

With diphenylphosphoranyl azide; sodium hydride; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;