cis-2β,3β-decahydronaphthalenediol

Base Information

• Chemical Name: cis-2β,3β-decahydronaphthalenediol
• CAS No.: 99015-03-9
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.252
• Mol file: 99015-03-9.mol

Synonyms:cis-2β,3β-decahydronaphthalenediol

Chemical Property of cis-2β,3β-decahydronaphthalenediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-2β,3β-decahydronaphthalenediol

There total 34 articles about cis-2β,3β-decahydronaphthalenediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

trans-2,3-octalin (2001-50-5) → 4aαH,8aβH-decahydronaphthalene-2α,3α-diol (18317-58-3,20835-18-1,20835-21-6,42177-35-5,56155-80-7,57397-07-6,99015-03-9,99015-04-0)

Guidance literature:

With sodium hydroxide; potassium permanganate; In water; tert-butyl alcohol; at -10 - -5 ℃; for 0.0666667h;

Reference yield:

trans-decalin-2-one (4832-17-1,5779-29-3,5779-30-6,16021-08-2,52079-67-1,91684-29-6,91684-30-9,1579-21-1,143392-76-1) → 4aαH,8aβH-decahydronaphthalene-2α,3α-diol (18317-58-3,20835-18-1,20835-21-6,42177-35-5,56155-80-7,57397-07-6,99015-03-9,99015-04-0)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc, chlorotrimethylsilane / diethyl ether / 18 h

2: 75 percent / KMnO₄, NaOH / H₂O; 2-methyl-propan-2-ol / 0.07 h / -10 - -5 °C

With sodium hydroxide; potassium permanganate; chloro-trimethyl-silane; zinc; In diethyl ether; water; tert-butyl alcohol;

Reference yield:

→ 4aαH,8aβH-decahydronaphthalene-2α,3α-diol (18317-58-3,20835-18-1,20835-21-6,42177-35-5,56155-80-7,57397-07-6,99015-03-9,99015-04-0)

Guidance literature:

With hydrogenchloride; at 130 ℃;

upstream raw materials:

(+/-)-3c-acetoxy-(4ar,8ac)-octahydro-naphthalen-2-one

4aαH,8aβH-decahydronaphthalene-2α,3α-diol

(+/-)-trans-octahydro-naphthalene-2,3-dione

trans-1,2,3,4,4a,5,6,8a-octahydronaphthalene

Downstream raw materials:

trans-cyclohexane-1,2-diacetic acid

2-cis,3-trans-Dihydroxy-(4a ref H,8a-trans H)-decalin

(+/-)-2c,3t-bis-(toluene-4-sulfonyloxy)-(4ar,8ac)-decahydro-naphthalene

trans-1,2-Bis-(2-oxoethyl)-cyclohexan