Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

Base Information

Chemical Name:Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester
CAS No.:119295-20-4
Molecular Formula:C₂₁H₁₉F₃N₂O₅
Molecular Weight:436.387
Hs Code.:

Synonyms:Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

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Technology Process of Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

There total 2 articles about Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 119295-22-6
2-Trifluoromethyl-1-trimethylsilanyl-1H-benzoimidazole

: 109629-23-4
Benzoic acid 2-acetoxy-1-acetoxymethoxymethyl-ethyl ester

: 119295-20-4
Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

Guidance literature:: With tin(IV) chloride; In acetonitrile; at 20 ℃; for 5h;
DOI:10.1007/BF00755691

Reference yield:

: 312-73-2
2-Trifluoromethylbenzimidazole

: 119295-20-4
Benzoic acid 1-acetoxymethyl-2-(2-trifluoromethyl-benzoimidazol-1-ylmethoxy)-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hexamethyldisilazane / 2 h / Heating

2: 45 percent / SnCl₄ / acetonitrile / 5 h / 20 °C

With tin(IV) chloride; 1,1,1,3,3,3-hexamethyl-disilazane; In acetonitrile;
DOI:10.1007/BF00755691