(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

Base Information

Chemical Name:(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide
CAS No.:230962-01-3
Molecular Formula:C₃₀H₃₉NO₇
Molecular Weight:525.642
Hs Code.:

Synonyms:(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

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Chemical Property of (2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

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Technology Process of (2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

There total 10 articles about (2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: (2R,4E)-N-{(1S)-1-[(benzyloxy)carbonyl]-2,2-dimethylpropyl}-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pent-4-enamide

: 230962-01-3
(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 5.75h; under 2250.23 Torr;

Reference yield:

: 230962-55-7
(2R)-N-{(1S)-1-[(benzyloxy)carbonyl]-2,2-dimethylpropyl}-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]pent-4-enamide

: 230962-01-3
(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 16 h / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / ethanol / 5.75 h / 20 °C / 2250.23 Torr

With hydrogen; palladium 10% on activated carbon; In ethanol; acetonitrile;

Reference yield:

: 230961-87-2
4-iodo-1-(3-methoxyphenyl)-2-methylbenzene

: 230962-01-3
(2R)-N-[(1S)-1-(carboxy)-2,2-dimethylpropyl]-2-[(4S)-2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl]-5-(3'-methoxy-2-methylbiphen-4-yl)pentanamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 16 h / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / ethanol / 5.75 h / 20 °C / 2250.23 Torr

With hydrogen; palladium 10% on activated carbon; In ethanol; acetonitrile;