trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline
CAS No.:128669-17-0
Molecular Formula:C₂₃H₂₀F₃N
Molecular Weight:367.414
Hs Code.:

Synonyms:trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Suppliers and Price of trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

There total 5 articles about trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 622-97-9,24936-41-2
1-ethenyl-4-methylbenzene

: 110972-17-3
N-(1-Methoxy-2,2,2-trifluoroethyl)diphenylamine

: 128669-17-0
trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With titanium tetrachloride; In dichloromethane; at -78 ℃;
DOI:10.3987/COM-89-5295

Reference yield:

: 622-97-9,24936-41-2
1-ethenyl-4-methylbenzene

: 110972-17-3
N-(1-Methoxy-2,2,2-trifluoroethyl)diphenylamine

: 128669-17-0
trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

: cis-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With titanium tetrachloride; In dichloromethane; at -78 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo00082a018

Reference yield:

: 110972-14-0
N-(phenyl)-N-(2,2,2-trifluoroethyl)benzenamine

: 128669-17-0
trans-1-Phenyl-4-(p-tolyl)-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 0.34 M KOH / Ambient temperature; electrolysis: carbon anode and Pt cathode; constant current 13.9 mA/cm²; charge passed: 7.8 F/mol

2: TiCl₄ / CH₂Cl₂ / 1 h / -78 °C

With potassium hydroxide; titanium tetrachloride; In dichloromethane;
DOI:10.1021/jo00082a018