Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Base Information

Chemical Name:Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate
CAS No.:119947-98-7
Molecular Formula:C₂₀H₂₅IO₈
Molecular Weight:520.318
Hs Code.:

Synonyms:Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Suppliers and Price of Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

There total 10 articles about Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 119947-97-6
Methyl 3,4-dideoxy-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-α-D-arabino-oct-3-en-2-ulopyranoside carbamate

: 119947-98-7
Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Guidance literature:: With iodonium di(2,4,6-trimethylpyridine) perchlorate; In acetonitrile;
DOI:10.1021/jo00023a028

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 119947-98-7
Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) t-BuLi / 1.) THF, -78 to 0 deg C, 4 h, 2.) 0 to 25 deg C, 12 h

2: (n-Bu)4NF / tetrahydrofuran / 12 h / 25 °C

3: 1.) t-BuOOH, VO(acac)2, 2.) Ag₂O / 1.) CH₂Cl₂, 25 deg C, 6 h, 2.) 25 deg C, 24 h

4: K-Selectride / tetrahydrofuran / 0.5 h / -78 °C

5: 2.) K₂CO₃ / 1.) CH₂Cl₂, 2.) MeOH, H₂O

6: 1.) I(Collidine)2ClO₄, 2.) H₂O / 1.) MeCN, 72 h, 2.) 12 h

With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium; iodonium(di-γ-collidine) perchlorate; tetrabutyl ammonium fluoride; water; tert.-butyl lithium; potassium tri-sec-butyl-borohydride; potassium carbonate; silver(l) oxide; In tetrahydrofuran;
DOI:10.1021/ja00188a060

Reference yield:

: 119947-92-1
*,R^*)>-(2,2-Dimethyl-α-(2-furanyl)-1,3-dioxolan-4-yl)methyl tert-butyldimethylsilyl ether

: 119947-98-7
Methyl 3-deoxy-3-iodo-7,8-O-(1-methylethylidene)-1-O-(phenylmethyl)-D-glycero-α-D-galacto-2-octulopyranoside cyclic carbonate

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) t-BuLi / 1.) THF, -78 to 0 deg C, 4 h, 2.) 0 to 25 deg C, 12 h

2: (n-Bu)4NF / tetrahydrofuran / 12 h / 25 °C

3: 1.) t-BuOOH, VO(acac)2, 2.) Ag₂O / 1.) CH₂Cl₂, 25 deg C, 6 h, 2.) 25 deg C, 24 h

4: K-Selectride / tetrahydrofuran / 0.5 h / -78 °C

5: 2.) K₂CO₃ / 1.) CH₂Cl₂, 2.) MeOH, H₂O

6: 1.) I(Collidine)2ClO₄, 2.) H₂O / 1.) MeCN, 72 h, 2.) 12 h

With tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium; iodonium(di-γ-collidine) perchlorate; tetrabutyl ammonium fluoride; water; tert.-butyl lithium; potassium tri-sec-butyl-borohydride; potassium carbonate; silver(l) oxide; In tetrahydrofuran;
DOI:10.1021/ja00188a060