tert-Butyl (5-amino-2-fluorobenzyl)carbamate

Base Information

Chemical Name:tert-Butyl (5-amino-2-fluorobenzyl)carbamate
CAS No.:209899-48-9
Molecular Formula:C₁₂H₁₇FN₂O₂
Molecular Weight:240.278
Hs Code.:
DSSTox Substance ID:DTXSID90701771
Wikidata:Q82633540
Mol file:209899-48-9.mol

Synonyms:209899-48-9;tert-Butyl (5-amino-2-fluorobenzyl)carbamate;3-[(Boc-amino)methyl]-4-fluoroaniline;TERT-BUTYL 5-AMINO-2-FLUOROBENZYLCARBAMATE;tert-butyl N-[(5-amino-2-fluorophenyl)methyl]carbamate;starbld0048254;SCHEMBL545381;DTXSID90701771;AC8135;MFCD09263964;AB50276;SY250015;CS-0088665;tert-Butyl [(5-amino-2-fluorophenyl)methyl]carbamate

Suppliers and Price of tert-Butyl (5-amino-2-fluorobenzyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-5-AMINO-2-FLUOROBENZYLCARBAMATE 95.00%
5MG
$ 504.81

AK Scientific
Tert-Butyl(5-amino-2-fluorobenzyl)carbamate
1g
$ 1207.00

Total 4 raw suppliers

Chemical Property of tert-Butyl (5-amino-2-fluorobenzyl)carbamate

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:240.12740595
Heavy Atom Count:17
Complexity:266

Purity/Quality:

98%min ^*data from raw suppliers

TERT-BUTYL-5-AMINO-2-FLUOROBENZYLCARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC1=C(C=CC(=C1)N)F

Technology Process of tert-Butyl (5-amino-2-fluorobenzyl)carbamate

There total 1 articles about tert-Butyl (5-amino-2-fluorobenzyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 903556-34-3
C₂₀H₂₃FN₂O₄

: 209899-48-9
C₁₂H₁₇FN₂O₂

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 17h;

Reference yield: 67.0%

: 209899-48-9
C₁₂H₁₇FN₂O₂

: 5231-87-8
3,4-diethoxy-3-cyclobuten-1,2-dione

: 903556-35-4
C₁₈H₂₁FN₂O₅

Guidance literature:: In ethanol; for 14h; Heating / reflux;

Reference yield:

: 209899-48-9
C₁₂H₁₇FN₂O₂

: 1221447-98-8
5-(but-2-yn-1-yloxy)pyrazine-2-carboxylic acid

: 1248503-66-3
C₂₁H₂₃FN₄O₄

Guidance literature:: C₁₂H₁₇FN₂O₂; 5-(but-2-yn-1-yloxy)pyrazine-2-carboxylic acid; With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

With potassium carbonate; In ethyl acetate;