2-hydroxy-5-methoxybenzenepropanoic acid

Base Information

• Chemical Name: 2-hydroxy-5-methoxybenzenepropanoic acid
• CAS No.: 225791-33-3
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.203
• Mol file: 225791-33-3.mol

Synonyms:2-hydroxy-5-methoxybenzenepropanoic acid

Chemical Property of 2-hydroxy-5-methoxybenzenepropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-hydroxy-5-methoxybenzenepropanoic acid

There total 2 articles about 2-hydroxy-5-methoxybenzenepropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-methoxy-3,4-dihydrocoumarin (20920-98-3) → 2-hydroxy-5-methoxybenzenepropanoic acid (225791-33-3)

Guidance literature:

With PPA; at 80 ℃; for 3h;

DOI:10.1071/C98023

Reference yield:

6-methoxycoumarin (17372-53-1) → 2-hydroxy-5-methoxybenzenepropanoic acid (225791-33-3)

Guidance literature:

With sodium hydroxide; sodium amalgam;

Reference yield:

2-hydroxy-5-methoxybenzenepropanoic acid (225791-33-3) + dimethyl sulfate (77-78-1) → 3-(2,5-dimethoxyphenyl)propanoic acid (10538-49-5)

Guidance literature:

upstream raw materials:

6-methoxycoumarin

6-methoxy-3,4-dihydrocoumarin

Downstream raw materials:

3-(2,5-dimethoxyphenyl)propanoic acid