2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene

Base Information

• Chemical Name: 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene
• CAS No.: 100938-86-1
• Molecular Formula: C₁₉H₂₉P
• Molecular Weight: 288.413
• Mol file: 100938-86-1.mol

Synonyms:2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene

Chemical Property of 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene

There total 14 articles about 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2,2-dichloro-1-(2,4,6-tri-tert-butylphenyl)-1-phosphaethene (100281-24-1) → 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene (100938-86-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In benzene; at 20 ℃; for 12h;

DOI:10.1016/S0040-4039(00)79577-3

Reference yield: 70.0%

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine] (100281-23-0) → 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene (100938-86-1)

Guidance literature:

With tetraethylammonium iodide; triphenylphosphine; zinc; dibromobis(triphenylphosphine)nickel(II); In tetrahydrofuran; for 24h; Heating;

DOI:10.1002/anie.200351727

Reference yield: 53.0%

E-2-chloro-1-(2,4,6-tri-t-butylphenyl)-1-phospha-ethylene (92957-42-1,92957-44-3,100281-30-9) → 2-(2,4,6-tri-tert-butylphenyl)phosphaacetylene (100938-86-1)

Guidance literature:

With tert.-butyl lithium; In tetrahydrofuran; -78 deg C, 40 min. then room temp.;

DOI:10.1246/cl.1988.1733

upstream raw materials:

Tris(trimethylsilyl)phosphane

2,4,6-tri-tert-butylbenzoyl chloride

trimethylsilyl iodide

(Diiodomethylene)(2,4,6-tri-tert-butylphenyl)phosphine

Downstream raw materials:

Phenyl(2,4,6-tri-t-butylphenyl)acetylene

1-(2',4',6'-tri-tert-butylphenyl)acetylene

1-tert-butyl-3-methyl-2,4-bis(2,4,6-tri-tert-butylphenyl)-1,3-diphosphacyclobutane-2,4-diyl

1-diisopropylamino-3-methyl-1,3-diphosphacyclobutane-2,4-diyl