3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester

Base Information

• Chemical Name: 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester
• CAS No.: 1044271-97-7
• Molecular Formula: C₁₄H₁₉NO₆S
• Molecular Weight: 329.374
• Mol file: 1044271-97-7.mol

Synonyms:3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester

Chemical Property of 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester

Chemical Property:

Purity/Quality:

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Technology Process of 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester

There total 1 articles about 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.5%

3-amino-5-(methylsulfonyl)-benzoic acid methyl ester (168618-23-3) + di-tert-butyl dicarbonate (24424-99-5) → 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester (1044271-97-7)

Guidance literature:

With dmap; triethylamine; In 1,4-dioxane; for 2h; Reflux;

Reference yield: 84.0%

3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester (1044271-97-7) → 3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid (1044271-98-8)

Guidance literature:

3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid methylester; With sodium hydroxide; water; In 1,4-dioxane; at 20 ℃;

With citric acid; In water; pH=4;

upstream raw materials:

3-amino-5-(methylsulfonyl)-benzoic acid methyl ester

di-tert-butyl dicarbonate

Downstream raw materials:

3-tert-butoxycarbonylamino-5-(methylsulfonyl)-benzoic acid

Refernces