S-(4-chlorophenyl) phenylcarbamothioate

Base Information

• Chemical Name: S-(4-chlorophenyl) phenylcarbamothioate
• CAS No.: 64651-83-8
• Molecular Formula: C13H10 Cl N O S
• Molecular Weight: 263.748
• Mol file: 64651-83-8.mol

Synonyms:Carbamothioicacid, phenyl-, S-(4-chlorophenyl) ester (9CI); NSC 30763; S-(4-Chlorophenyl)N-phenylthiocarbamate

Chemical Property of S-(4-chlorophenyl) phenylcarbamothioate

Chemical Property:

• Density: 1.34g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-(4-chlorophenyl) phenylcarbamothioate

There total 8 articles about S-(4-chlorophenyl) phenylcarbamothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4,4'-dichlorodiphenyl disulfide (1142-19-4) + phenyl isocyanate (103-71-9) → phenyl-thiocarbamic acid (S)-4-chlorophenyl ester (64651-83-8)

Guidance literature:

4,4'-dichlorodiphenyl disulfide; With aluminium trichloride; zinc; In water; acetonitrile; at 65 ℃; for 1.5h;

phenyl isocyanate; In water; acetonitrile; at 65 ℃; for 0.583333h;

DOI:10.1246/cl.2005.1330

Reference yield: 88.0%

phenyl isocyanate (103-71-9) + p-Chlorothiophenol (106-54-7) → phenyl-thiocarbamic acid (S)-4-chlorophenyl ester (64651-83-8)

Guidance literature:

In dichloromethane; at 25 ℃; for 1h;

DOI:10.1007/s00706-007-0762-7

Reference yield: 84.0%

chloro-thioformic acid (4-chloro-phenyl)ester (13606-10-5) + aniline (62-53-3) → phenyl-thiocarbamic acid (S)-4-chlorophenyl ester (64651-83-8)

Guidance literature:

In dichloromethane; for 1.25h; Heating;

DOI:10.1080/00304940609356001

upstream raw materials:

phenyl isocyanate

p-Chlorothiophenol

chloro-thioformic acid (4-chloro-phenyl)ester

aniline

Downstream raw materials:

N-(4-metoxyphenyl)-N'-phenylurea

N-(4-chlorophenyl)-N'-phenylurea

N-phenyl-N'-benzylurea

p-Chlorothiophenol

Refernces

• 1、 Movassagh, Barahman,Soleiman-Beigi, Mohammad. "Synthesis of thiocarbamates from thiols and isocyanates under catalyst- and solvent-free conditions". . p. 137 - 140. Retrieved 2008/09/20.
• 2、 Zhang, Xiao-Peng,Lu, Shi-Wei. "A selenium-catalysed synthesis of thiocarbamates from nitroarenes, carbon monoxide and thiols under mild conditions". experimental part. p. 589 - 591. Retrieved 2009/08/15.